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Lazanda Savings Card,
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* Some exclusions apply.
Please see Terms & Conditions below.

Please see Important Safety Information and Medication Guide, including BOXED WARNING.

Important Safety Information

Lazanda (La-ZAN-da) (fentanyl) nasal spray is a prescription medicine used to manage breakthrough pain in adults with cancer (18 years of age and older) who are already routinely taking other opioid pain medicines around-the-clock for cancer pain.


Do not use Lazanda unless you are regularly using another opioid pain medicine around-the-clock for your cancer pain and your body is used to these medicines (this means that you are opioid tolerant). You can ask your healthcare provider if you are opioid tolerant.

Keep Lazanda in a safe place away from children.

Get emergency medical help right away if:

  • a child takes Lazanda. Lazanda can cause an overdose and death in any child who takes it
  • an adult who has not been prescribed Lazanda takes it
  • an adult who is not already taking opioids around-the-clock takes Lazanda

These are medical emergencies that can cause death.

Always keep Lazanda in a safe place away from children and from anyone for whom it has not been prescribed.

Lazanda can cause life-threatening breathing problems that can lead to death:

  • Do not take Lazanda if you are not opioid tolerant. (Opioid tolerant means that you are already taking other opioid (narcotic) pain medicines around-the-clock for your cancer pain and your body is used to these medicines).
  • If you stop taking your around-the-clock opioid pain medicine for your cancer, you must stop taking Lazanda. You may no longer be opioid tolerant. Talk to your healthcare provider about how to treat your pain.
  • Take Lazanda exactly as prescribed by your healthcare provider. You must not take more than 1 dose of Lazanda for each episode of breakthrough cancer pain. You must wait two hours before treating a new episode of breakthrough cancer pain with Lazanda.
  • Do not switch from Lazanda to other medicines that contain fentanyl without talking with your healthcare provider. The amount of fentanyl in a dose of Lazanda is not the same as the amount of fentanyl in other medicines that contain fentanyl. Your healthcare provider will prescribe a starting dose of Lazanda that may be different than other fentanyl-containing medicine you may have been taking.
  • Never give Lazanda to anyone else, even if they have the same symptoms you have. It may harm them or even cause death.

Do not take Lazanda:

Lazanda is available only through a program called the TIRF REMS ACCESS program. Talk to your healthcare provider for more information.

Before taking Lazanda, tell your healthcare provider if you:

Tell your healthcare provider about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. Some medicines may cause serious or life-threatening medical problems when taken with Lazanda. Sometimes, the doses of certain medicines and Lazanda need to be changed if used together.

Possible side effects of Lazanda:

Call your healthcare provider or get emergency medical help right away if you:

These symptoms can be a sign that you have taken too much Lazanda or the dose is too high for you. These symptoms may lead to serious problems or death if not treated right away. If you have any of these symptoms, do not take any more Lazanda until you have talked to your healthcare provider.

The most common side effects of Lazanda seen in clinical studies are:

Constipation (not often enough or hard bowel movements) is a very common side effect of pain medicines (opioids) including Lazanda and is unlikely to go away without treatment. Talk to your healthcare provider about dietary changes and the use of laxatives (medicines to treat constipation) and stool softeners to prevent or treat constipation while taking Lazanda.

These are not all the possible side effects of Lazanda. Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

For more information ask your doctor or pharmacist; or download the Medication Guide and the complete full Prescribing Information for Lazanda, which includes a Boxed Warning.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit; or call 1-800-FDA-1088. You can also report side effects to Depomed by calling 1-866-458-6389.

* Available to commercially insured patients only. Cash-paying patients and patients covered by Medicare, Medicaid, or any other state- or federally-funded benefit program are excluded. Patients must be 18 years of age or older. This promotion cannot be combined with any other programs, offers, or discount. Depomed reserves the right to rescind, revoke, or amend this offer without further notice.

Co-pay Help Terms and Conditions

The Lazanda Signature Support program is available to help patients with any issues they may have in obtaining Lazanda, including prior authorizations from their insurance companies as well as how to save on their out-of-pocket costs for Lazanda.

Here is how the program works:

Terms and Conditions

If you have questions about using the co-pay savings card, please call 1-855-859-2970. For benefit verification or help with prior authorization, please call Signature Support at 1-855-775-2762 toll-free or email

Patient instructions: Redeem this co-pay savings card ONLY when it is accompanied by a valid prescription for Lazanda. This offer is not valid for cash-paying patients or prescriptions covered by or submitted for reimbursement under Medicaid, Medicare, or similar federal or state programs. Please see specific eligibility requirements above.

If you are a new patient with a prescription for 5 bottles or less, please present your co-pay card for a $0 co-pay that is good for up to 3 refills during the first month of treatment, for a total of up to 10 bottles. If your prescription is for over 5 bottles of Lazanda, you pay $5 (up to a maximum benefit of $625) for the first and each additional month.

Pharmacist instructions for a patient with an eligible third party ($0 co-pay): Submit the claim to the primary third-party payer first, then submit the balance due to Therapy First Plus as a secondary payer as co-pay using a valid Other Coverage Code: use 8 to reduce the co-pay expense, or 3 if primary has denied coverage. The patient can receive up to 10 bottles at no more than 5 bottles per fill, at a $0 co-pay for the first 30 days, good for up to 3 fills. If the patient's insurance requires prior authorization, please initiate the prior authorization process by calling, or instructing the patient to call, the Signature Support line at 1-855-775-2762; this will help the patient to gain access to Lazanda and to save on additional prescriptions. Reimbursement will be received from Therapy First Plus. For any questions regarding Therapy First Plus online processing, please call the Help Desk at 1-800-422-5604.

Eligibility: This offer is valid for commercially insured patients who are 18 years of age or older. Offer expires on June 30, 2015. This program cannot be combined with any other programs, offers, or discounts. Program managed by PSKW, LLC on behalf of Depomed, Inc. Void where taxed, restricted, or prohibited by law. Product dispensed pursuant to program rules and federal and state laws. The parties reserve the right to amend or end this program at any time without notice.